Ratio AB 1–42/40 | pTau | tTau | Hippocampal volume | ||||||
---|---|---|---|---|---|---|---|---|---|
Beta (95%CI) | p-value | Beta (95%CI) | p-value | Beta (95%CI) | p-value | Beta (95%CI) | p-value | ||
BMO-MRW | TS | 3.22E−5 (− 5.12E−5 to 11.6E−5) | 0.444 | − 0.07 (− 0.16 to 0.02) | 0.111 | − 042 (− 0.92 to 0.07) | 0.092 | 0.26 (− 1.03 to 1.56) | 0.688 |
T | 2.82E−5 (− 8.35E−5 to 14.0E−5) | 0.503 | − 0.02 (− 0.14 to 0.11) | 0.812 | − 0.14 (− 0.81 to 0.54) | 0.687 | 0.40 (− 1.36 to 2.16) | 0.651 | |
TI | 3.16E−5 (− 5.08E−5 to 11.4E−5) | 0.448 | 0.01 (− 0.08 to 0.10) | 0.800 | − 0.01 (− 0.51 to 0.49) | 0.968 | 0.49 (− 0.80 to 1.79) | 0.448 | |
NI | 2.4E−5 (− 4.84E−5 to 9.71E−5) | 0.006 | 0.02 (− 0.06 to 0.10) | 0.672 | 0.07 (− 0.37 to 0.51) | 0.756 | 0.80 (− 0.32 to 1.92) | 0.158 | |
N | 4.04E−5 (− 3.06E−5 to 11.1E−5) | 0.261 | − 0.03 (− 0.11 to 0.05) | 0.425 | − 0.21 (− 0.63 to 0.22) | 0.336 | 0.99 (− 0.09 to 2.07) | 0.071 | |
NS | 6.64E−5 (− 3.06 to 13.5E−5) | 0.056 | − 0.07 (− 0.15 to 0.01) | 0.073 | − 0.56 (− 0.78 to 0.07) | 0.099 | 0.76 (− 0.37 to 1.89) | 0.183 | |
RNFL | TS | − 9.23E−5 (− 32.5E−5 to 14.1E−5) | 0.434 | 0.08 (− 0.18 to 0.34) | 0.561 | 0.49 (− 0.90 to 1.88) | 0.485 | 1.18 (− 2.63 to 4.98) | 0.539 |
T | − 13.8E−5 (− 0.001 to 27.1E−5) | 0.505 | 0.32 (− 0.12 to 0.78) | 0.150 | 2.22 (− 0.18 to 4.61) | 0.069 | − 0.19 (− 7.00 to 6.60) | 0.954 | |
TI | 7.68E−5 (− 10.7E−5 to 26.1E−5) | 0.408 | − 0.17 (− 0.37 to 0.04) | 0.108 | − 0.97 (− 2.05 to 0.11) | 0.076 | 3.77 (0.90 to 6.63) | 0.011* | |
NI | 5.71E−5 (− 11.0E−5 to 22.5E−5) | 0.500 | − 0.15 (− 0.33 to 0.04) | 0.120 | − 1.02 (− 2.00 to −0.41) | 0.041 | 3.38 (0.75 to 6.01) | 0.013* | |
N | 5.08E−5 (− 23.7E−5 to 33.8E−5) | 0.726 | − 0.04 (− 0.36 to 0.28) | 0.813 | − 0.76 (− 2.47 to 0.94) | 0.337 | 6.81 (2.45 to 11.17) | 0.003* | |
NS | 0.00 (− 7.63E−5 to 31.5E−5) | 0.228 | − 0.10 (− 0.32 to 0.12) | 0.364 | − 0.71 (− 1.87 to 0.46) | 0.232 | 4.25 (0.96 to 7.54) | 0.012* | |
CGL | TS 1 | − 1.94E−5 (− 0.001 to 0.001) | 0.959 | − 0.53 (− 1.36 to 0.29) | 0.200 | − 2.26 (− 6.70 to 2.18) | 0.314 | 17.13 (5.69 to 25.57) | 0.004 |
TS 2 | − 8.72E−5 (− 0.001 to 0.001) | 0.823 | − 0.37 (− 1.23 to 0.48) | 0.390 | − 1.97 (− 6.57 to 2.64) | 0.398 | 15.58 (3.54 to 27.62) | 0.012* | |
NS 3 | 0.00 (− 0.001 to 0.001) | 0.722 | − 0.12 (− 1.09 to 0.86) | 0.811 | − 0.88 (− 6.13 to 4.36) | 0.738 | 17.85 (3.89 to 31.81) | 0.013* | |
NS 4 | 0.00 (− 0.001 to 0.001) | 0.744 | − 0.12 (− 1.13 to 0.89) | 0.812 | − 0.73 (− 6.14 to 4.67) | 0.788 | 17.33 (2.51 to 32.16) | 0.023* | |
TS 5 | 4.14E−5 (− 0.001 to 0.001) | 0.902 | − 0.41 (− 1.15 to 0.32) | 0.268 | − 2.61 (− 6.56 to 1.35) | 0.193 | 14.66 (4.58 to 24.74) | 0.005* | |
TS 6 | 0.00 (0.000 to 0.001) | 0.123 | − 0.78 (− 1.49 to −0.07) | 0.032 | − 3.57 (− 7.42 to 0.28) | 0.069 | 4.23 (− 6.25 to 14.70) | 0.424 | |
NS 7 | 0.00 (0.000 to 0.001) | 0.193 | − 0.65 (− 1.36 to 0.05) | 0.070 | − 3.25 (− 7.07 to 0.57) | 0.094 | 6.08 (− 4.28 to 16.44) | 0.246 | |
NS 8 | − 1.56E−5 (− 0.001 to 0.001) | 0.971 | − 0.44 (− 1.40 to 0.52) | 0.361 | − 3.08 (− 8.21 to 2.05) | 0.235 | 18.93 (5.68 to 32.19) | 0.006* | |
TI 9 | 0.00 (0.000 to 0.001) | 0.516 | − 0.88 (− 1.69 to −0.08) | 0.032 | − 4.76 (− 9.07 to −0.44) | 0.031 | 13.26 (1.75 to 24.77) | 0.025* | |
TI 10 | 0.00 (− 0.001 to 0.001) | 0.726 | − 0.46 (− 1.21 to 0.28) | 0.219 | − 1.49 (− 5.51 to 2.54) | 0.465 | 2.79 (− 8.02 to 13.62) | 0.608 | |
NI 11 | 0.00 (0.000 to 0.001) | 0.705 | − 0.37 (− 1.04 to 0.31) | 0.285 | − 1.61 (− 5.25 to 2.04) | 0.384 | 4.06 (− 5.70 to 13.82) | 0.410 | |
NI 12 | 0.00 (− 0.001 to 0.001) | 0.480 | − 0.69 (− 1.63 to 0.26) | 0.150 | − 3.87 (− 8.94 to 1.19) | 0.132 | 13.53 (0.01 to 27.05) | 0.050 | |
TI 13 | 0.00 (− 0.001 to 0.001) | 0.494 | − 1.04 (− 2.05 to −0.02) | 0.045 | − 5.43 (− 10.89 to 0.03) | 0.051 | 20.42 (5.70 to 35.14) | 0.007* | |
TI 14 | 0.00 (− 0.001 to 0.001) | 0.567 | − 0.81 (− 1.70 to 0.08) | 0.073 | − 4.65 (− 9.42 to 0.11) | 0.055 | 16.39 (3.68 to 29.10) | 0.012* | |
TI 15 | 3.81E−5 (− 0.001 to 0.001) | 0.926 | − 0.75 (− 1.65 to 0.14) | 0.097 | − 4.38 (− 9.17 to 0.41) | 0.073 | 14.24 (1.37 to 27.12) | 0.031* | |
TI 16 | 0.00 (− 0.001 to 0.001) | 0.458 | − 0.70 (− 1.65 to 0.25) | 0.146 | − 3.43 (− 8.54 to 1.69) | 0.187 | 16.04 (2.23 to 29.85) | 0.023* |