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Table 7 NPIK Sleep Disturbance Score—adjusted analysis stratified by CDR statusa

From: APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia

 

β

SE

p

CDR score 0/0.5, n=67

APOE ε4 statusb

  Heterozygous

1.21

0.60

0.048

  Homozygous

0.13

2.17

0.952

CDR score 1/2/3, n=142

APOE ε4 statusb

  Heterozygous

0.10

0.80

0.897

  Homozygous

2.77

1.93

0.048

  1. aAdjusted by age, gender, APOE ε2 status, NPI-D, NPI-E and NIA-AA ABC score
  2. bBaseline reference APOE ε3/ε3, ε2/ε3 or ε2/ε2