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Table 6 NPIK Sleep Disturbance Score—adjusted analysis stratified by neuropathological changea

From: APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia

  β SE p
ABC score 0/1 (“None”/“Low), n=80
APOE ε4 statusb
  Heterozygosity 0.97 0.75 0.200
  Homozygosity NA‡ NA‡ NA‡
ABC Score 2/3 (“Intermediate”/“High”), n=129
APOE ε4 statusb
  Heterozygous 0.42 0.83 0.609
  Homozygous 2.85 1.40 0.045
  1. a Adjusted by age, gender, APOE ε2 status, NPI-D, NPI-E and CDR-SOB
  2. b Baseline reference APOE ε3/ε3, ε2/ε3 or ε2/ε2
  3. No participants within the ABC 0/1 group with 2 APOE ε4 alleles