Skip to main content

Table 6 NPIK Sleep Disturbance Score—adjusted analysis stratified by neuropathological changea

From: APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia

 

β

SE

p

ABC score 0/1 (“None”/“Low), n=80

APOE ε4 statusb

  Heterozygosity

0.97

0.75

0.200

  Homozygosity

NA‡

NA‡

NA‡

ABC Score 2/3 (“Intermediate”/“High”), n=129

APOE ε4 statusb

  Heterozygous

0.42

0.83

0.609

  Homozygous

2.85

1.40

0.045

  1. a Adjusted by age, gender, APOE ε2 status, NPI-D, NPI-E and CDR-SOB
  2. b Baseline reference APOE ε3/ε3, ε2/ε3 or ε2/ε2
  3. No participants within the ABC 0/1 group with 2 APOE ε4 alleles