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Table 5 NPIK Global Sleep Disturbance Score—full population linear regression

From: APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia

Full population n=202

 

Crude analysis

Adjusted analysis

β

SE

p

β

SE

p

APOE ε4 Statusa

Heterozygous

0.67

0.54

0.221

0.41

0.57

0.471

Homozygous

3.18

1.20

0.008

2.53

1.18

0.034

NIA-AA ABC Stageb

Low

   

0.51

0.94

0.590

Intermediate

   

0.07

1.04

0.943

High

   

-0.73

1.05

0.493

APOE ε2 carrier status

   

1.43

1.24

0.252

Age

   

-0.08

0.03

0.004

Male gender

   

-0.53

0.50

0.293

NPI-D Global Score (depression)

   

0.01

0.14

0.928

NPI-E Global Score (anxiety)

   

0.19

0.13

0.145

CDR-SOB

   

0.13

0.04

0.003

  1. a Baseline Reference of APOE ε3/ε3, ε2/ε3, and ε2/ε2
  2. b Baseline reference of NIA-AA ABC Score ‘None’