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Table 3 Baseline demographics by APOE-ε4 status

From: APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia

 

Non ε4 carrier

n=96

ε4 heterozygosity

n=95

ε4 homozygosity

n=11

p value

Mean age (SD)

85.2 (9.1)

83.0 (9.3)

81.5 (8.5)

0.162*

Gender male no. (%)

48 (50.0)

49 (51.6)

6 (54.5)

0.948†

ABC stage

None

16

3

0

<0.001†

Low

41

18

0

Intermediate

15

23

4

High

24

51

7

Mean MMSE (SD)

16.1 (12.5)

12.2 (11.0)

9.0 (9.8)

0.063*

Mean CDR Global Score (SD)

1.6 (1.3)

2.0 (1.2)

2.8 (0.8)

0.002*

Mean CDR SOB

8.8 (8.0)

12.2 (6.8)

16.2 (5.1)

<0.001*

  1. *p values calculated by Kruskal-Wallis test
  2. Chi-squared Test