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Table 3 Baseline demographics by APOE-ε4 status

From: APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia

  Non ε4 carrier
n=96
ε4 heterozygosity
n=95
ε4 homozygosity
n=11
p value
Mean age (SD) 85.2 (9.1) 83.0 (9.3) 81.5 (8.5) 0.162*
Gender male no. (%) 48 (50.0) 49 (51.6) 6 (54.5) 0.948†
ABC stage
None 16 3 0 <0.001†
Low 41 18 0
Intermediate 15 23 4
High 24 51 7
Mean MMSE (SD) 16.1 (12.5) 12.2 (11.0) 9.0 (9.8) 0.063*
Mean CDR Global Score (SD) 1.6 (1.3) 2.0 (1.2) 2.8 (0.8) 0.002*
Mean CDR SOB 8.8 (8.0) 12.2 (6.8) 16.2 (5.1) <0.001*
  1. *p values calculated by Kruskal-Wallis test
  2. Chi-squared Test