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Table 1 Inclusion and exclusion criteria

From: APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia

Inclusion criteria Exclusion criteria
UK Brain Bank Network Participant
Recorded Braak, Thal and CERAD pathological stage
Each of the following within 12 months pre-mortem
Neuropsychiatry Inventory K measure of sleep disturbance
Clinical Dementia Rating (CDR) global score
Age > 50
Significant intracerebral pathology other than Alzheimer’s disease including the following:
Severe cerebrovascular disease (ischaemic and haemorrhagic)
Lewy body disease as defined by Braak LB stage > 0
Neoplasia, epilepsy, CNS inflammation, trauma, vascular malformation, prion disease
Pathological findings in keeping with dementia other than Alzheimer’s dementia including Frontotemporal dementia, vascular dementia and Lewy body dementias