From: Sex differences in neuropsychiatric symptoms in Alzheimer’s disease dementia: a meta-analysis
NPS | k | Hedges’ g [95% CI]a | z statistic | P | Q statistic | P Q statistic | I2 statistic |
---|---|---|---|---|---|---|---|
Total score NPS measure (outlier excluded) | 13 | 0.04 [− 0.04, 0.12] | 1.03 | 0.31 | 7.54 | 0.82 | 0.00 |
Depressive symptoms (outlier excluded) | 16 | 0.24 [0.14, 0.34] | 4.59 | < 0.001 | 30.15 | 0.02 | 44.29 |
Delusions (outlier excluded) | 10 | 0.19 [0.04, 0.34] | 2.53 | 0.01 | 19.99 | 0.02 | 58.78 |
Aberrant motor behavior (outlier excluded) | 9 | 0.17 [0.08, 0.26] | 3.56 | < 0.001 | 3.25 | 0.92 | 0.00 |
Anxiety (outlier excluded) | 10 | 0.11 [0.00, 0.22] | 1.98 | 0.05 | 13.27 | 0.01 | 25.15 |
Sleep disturbances | 6 | 0.11 [− 0.02, 0.24] | 1.62 | 0.11 | 5.66 | 0.34 | 21.77 |
Disinhibition (outlier excluded) | 10 | 0.08 [− 0.05, 0.21] | 1.16 | 0.25 | 17.01 | 0.05 | 46.48 |
Eating behavior | 6 | 0.07 [− 0.04, 0.18] | 1.28 | 0.20 | 3.23 | 0.67 | 0.00 |
Hallucinations (outlier excluded) | 10 | 0.07 [− 0.13, 0.26] | 0.65 | 0.51 | 36.63 | < 0.001 | 77.20 |
Agitation (outlier excluded) | 11 | 0.01 [− 0.07, 0.10] | 0.26 | 0.79 | 12.53 | 0.25 | 3.12 |
Irritability | 11 | 0.00 [− 0.08, 0.07] | − 0.10 | 0.92 | 14.91 | 0.14 | 0.00 |
Euphoria (outlier excluded) | 10 | 0.00 [− 0.10, 0.10] | − 0.04 | 0.97 | 8.10 | 0.52 | 14.55 |
Apathy (outlier excluded) | 11 | − 0.10 [− 0.18, − 0.01] | − 2.25 | 0.02 | 5.00 | 0.89 | 0.00 |