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Table 7 Serum Trx80 associations with ApoE4 and MMSE scores from the combined dataset

From: Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD

 

FINGER

SCI

MCI

AD

N

β (p)

N

β (p)

N

β (p)

N

β (p)

ApoE4 carriers (yes/no)

14/32

0.30 (0.05)

6/9

0.41 (0.50)

10/12

0.59 (0.02)

6/8

− 0.28 (0.55)

MMSE

47

0.21 (0.17)

25

− 0.05 (0.81)

23

− 0.41 (0.05)

25

− 0.03 (0.87)

  1. Values are standardized β coefficients (p values) from linear regression models with serum Trx80 levels as a dependent variable in FINGER and GEDOC cohorts. Linear regression models are adjusted for age. In ApoE4 regression models, a positive coefficient is interpreted as Trx80 being higher in ApoE4 carriers. p values considered significant (bold) if p < 0.05. N, number of participants with available data for each analysis