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Table 4 Associations between serum Trx80 and CSF AD biomarkers in the GEDOC cohort

From: Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD

 

Total

SCI

MCI

6AD

N

β (p)

N

β (p)

N

β (p)

N

β (p)

Aβ42

99

− 0.14 (0.23)

37

0.21 (0.38)

31

− 0.15 (0.50)

31

− 0.12 (0.56)

t-tau

99

0.12 (0.31)

37

− 0.36 (0.08)#

31

− 0.23 (0.29)

31

0.29 (0.17)

p-tau

99

0.13 (0.27)

37

− 0.48 (0.02)

31

− 0.03 (0.89)

31

0.27 (0.20)

p-tau/t-tau

99

− 0.07 (0.55)

37

− 0.07 (0.73)

31

0.41 (0.05)

31

− 0.21 (0.34)

  1. Values are standardized β coefficients (p values) from linear regression models with serum Trx80 levels as a dependent variable. Linear regressions are adjusted for age. p values considered significant (bold) if p < 0.05; #, p < 0.10. N, number of participants with available data for each analysis