Gene | Dataset | APOE ɛ2/ɛ3 | APOE ɛ3/ɛ3 | APOE ɛ3/ɛ4 | Total | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | Z-score | P-value | N | Z-score | P-value | N | Z-score | P-value | N | Z-score | P-value | ||
INPP5D | Blood | 26 | −0.62 | 0.53 | 102 | 1.67 | 0.10 | 31 | 2.12 | 0.03 | 179 | 2.16 | 0.03 |
Brain | 71 | 1.80 | 0.07 | 355 | 0.92 | 0.36 | 126 | 0.66 | 0.51 | 576 | 2.30 | 0.02 | |
Combined | 97 | 1.51 | 0.13 | 457 | 1.29 | 0.20 | 157 | 1.31 | 0.19 | 755 | 2.42 | 0.02 | |
HLA-DQA1 | Blood | 26 | −1.49 | 0.14 | 102 | −1.80 | 0.07 | 31 | 0.96 | 0.34 | 179 | −2.26 | 0.03 |
Brain | 71 | 0.30 | 0.76 | 355 | −3.13 | 1.7 × 10−3 | 126 | −1.01 | 0.31 | 576 | −2.23 | 0.03 | |
Combined | 97 | −0.16 | 0.87 | 457 | −2.84 | 4.6 × 10−3 | 157 | −0.66 | 0.51 | 755 | −2.42 | 0.02 | |
SPDYE3 | Blood | 26 | −0.08 | 0.94 | 102 | −0.76 | 0.45 | 31 | −0.96 | 0.34 | 179 | −1.47 | 0.14 |
Brain | 71 | −0.79 | 0.43 | 355 | −0.97 | 0.33 | 126 | −2.16 | 0.03 | 576 | −2.73 | 6.4 × 10−3 | |
Combined | 97 | −0.77 | 0.44 | 457 | −0.96 | 0.33 | 157 | −2.37 | 0.02 | 755 | −2.26 | 0.02 | |
TSPOAP1 | Blood | 26 | −1.38 | 0.17 | 102 | 0.30 | 0.77 | 31 | −0.16 | 0.87 | 179 | −0.55 | 0.58 |
Brain | 71 | −1.04 | 0.30 | 355 | −2.17 | 0.03 | 126 | −1.85 | 0.06 | 576 | −3.65 | 2.6 × 10−4 | |
Combined | 97 | −1.39 | 0.16 | 457 | −1.35 | 0.18 | 157 | −1.82 | 0.07 | 755 | −2.24 | 0.03 | |
SIGLEC11 | Blood | 26 | 1.43 | 0.15 | 102 | 0.47 | 0.64 | 31 | 0.24 | 0.81 | 179 | 0.33 | 0.74 |
Brain | 71 | 1.05 | 0.29 | 355 | 2.46 | 0.01 | 126 | 2.58 | 9.9 × 10−3 | 576 | 3.77 | 1.6 × 10−4 | |
Combined | 97 | 1.42 | 0.16 | 457 | 1.86 | 0.06 | 157 | 2.54 | 0.01 | 755 | 2.17 | 0.03 |