Fig. 3
From: Association of peripheral immunity with cognition, neuroimaging, and Alzheimer’s pathology
Mediation analyses with global cognition measured by ADAS, memory function, executive function as cognitive outcomes. a is the effect of independent variable on mediators; b is the effect of mediators on dependent variables after controlling the influence of independent variables; c is the total effect of independent variables on dependent variables; c’ is the direct effect of independent variables on dependent variables after controlling the influence of mediators; IE is the indirect effect of independent variables on dependent variables, in this intermediary model, c = c’ + ab. ADAS, Alzheimer's Disease Assessment Scale; MEM, memory function; EF, executive function, NEU, neutrophils; LYM, lymphocytes; NLR, neutrophil-lymphocyte ratio