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Table 1 Baseline characteristics of study population

From: Detection of plasma Aβ seeding activity by a newly developed analyzer for diagnosis of Alzheimer’s disease

Characteristic

AD (n=79)

NADD (n=64)

NC (n=75)

p

Man, n (%)

34 (43.0)

39 (60.9)

10 (13.3)

<0.001

Age, years

64.15±8.75

63.16±7.64

61.85±5.47

0.108

Education, years

11.11±4.07

9.15±4.64

13.48±2.91

<0.001

Disease duration, years

2.76±1.51

2.28±1.90

NA

<0.001

APOE ε4, n (%)

38 (55.1)

12 (19.4)

14 (18.7)

<0.001

MMSE

17.99±7.38

16.66±8.07

29.76±0.46

<0.001

MoCA

13.76±6.96

11.92±6.71

28.52±1.16

<0.001

CDR

1.42±0.92

1.49±0.97

0

<0.001

Aβ42, pg/ml

341.74±152.1

514.32±246.80

NA

<0.001

P-tau181, pg/ml

163.98±84.62

69.83±64.43

NA

<0.001

  1. Abbreviations: AD, Alzheimer’s disease; APOE, apolipoprotein E; CDR, clinical dementia rating; MMSE, Mini-Mental State Examination; MoCA, Montreal cognitive assessment; NADD, non-AD dementia; NA, not applicable; NC, normal cognition