Fig. 3
From: Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping
Overview of rs439401 frequencies and case-control association findings, comparing APOE filtering approach 1 to approach 2. A Carrier frequencies across both approaches for APOE*4/4 and APOE*3/4 WT vs HOM groups, as well as in the Haplotype reference consortium v1.1 (HRC). Note decreased frequencies for rs439401 in approach 2 that appear concordant with the HRC. B, C Overview of association findings for all evaluated strata, comparing B approach 1 to C approach 2. Significant effects are denoted by an asterisk (*). Error bars show 95% confidence intervals. Note loss of significant effects in approach 2