Fig. 7From: A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitroUptake of fluorescence-labeled D-peptides analyzed by confocal microscopy. 25 μM FAM-labeled peptides (ISAD1 and ISArev) were incubated with N2a cells expressing TauRDΔK for 24 h. The uptake of D-peptides was analyzed by confocal microscopy. As shown in the representative images, the peptides are mainly localized in the cytoplasm (A1, B1 Draq5 shown as red; A2 ISAD1-FAM, B2 ISAD1rev-FAM; A3, B3 merged images)Back to article page