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Table 2 Regression coefficients and corresponding weights

From: Cognitive composites for genetic frontotemporal dementia: GENFI-Cog

  C9orf72 GRN MAPT
Coef. Weight Coef. Weight Coef. Weight
Language
Camel and Cactus Test    − 0.004 0.003 − 0.04 0.04
Boston Naming Test      − 0.39 0.40
Category fluency − 0.13 0.09     
Attention and mental processing speed
Digit span forward       
Trail Making Test – part A       
Digit symbol       
D-KEFS CWIT – colour naming − 0.06 0.04    − 0.09 0.09
D-KEFS CWIT – word naming − 0.04 0.03 0.09a    
Executive function
Digit span backward       
Trail Making Test – part B − 0.07 0.05 − 0.28 0.23   
D-KEFS CWIT – ink naming − 0.29 0.20 − 0.24 0.20   
Phonemic fluency    0.24a    
Visuoconstruction
Benson figure copy − 0.09 0.06     
Memory
Benson figure recall    − 0.06 0.05 − 0.01 0.01
FCSRT free recall − 0.50 0.35    − 0.06 0.06
FCSRT total recall    − 0.05 0.04 − 0.30 0.31
FCSRT delayed free recall    − 0.16 0.13 − 0.01 0.01
FCSRT delayed total recall       
Social cognition
Facial Emotion Recognition Test − 0.26 0.18 − 0.42 0.35 − 0.08 0.08
  1. Data are presented as coefficients and weights. Coefficient gives the change in log odds of being a mutation carrier for each Z-score increase in the score on the cognitive test. Weight gives the weighting used when calculating the weighted cognitive composite score
  2. Abbreviations: C9orf72 chromosome 9 open reading frame 72, GRN progranulin, MAPT microtubule-associated protein tau, D-KEFS CWIT Delis-Kaplan Executive Function System Colour-Word Interference Test, FCSRT Free and Cued Selective Reminding Test
  3. aPositive coefficients indicate better performance in mutation carriers compared to controls and were not included in the composite score