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Table 3 Correlations of plasma LCN2 and CSF biomarkers in dementia groups

From: Plasma Lipocalin 2 in Alzheimer’s disease: potential utility in the differential diagnosis and relationship with other biomarkers

  t-tau p-tau Abeta42 Abeta40
AD
 rho −0.098 −0.112 0.182 0.070
 95% CI −0.332 to 0.147 −0.344 to 0.134 −0.406 to 0.062 −0.193 to 0.323
p-value 0.420 0.358 0.131 0.592
VaD
 rho 0.281 −0.141 −0.030  
 95% CI −0.114 to 0.600 −0.517 to 0.280 −0.438 to 0.389 n.a.
p-value 0.147 0.501 0.891  
LBD
 rho 0.078 −0.119 −0.296  
 95% CI −0.233 to 0.374 −0.444 to 0.233 −0.560 to 0.022 n.a.
p-value 0.617 0.495 0.060  
CJD
 rho −0.028 −0.071 0.105  
 95% CI −0.247 to 0.103 −0.372 to 0.243 −0.168 to 0.362 n.a.
p-value 0.798 0.651 0.439  
FTD
 rho −0.041 −0.148 0.031  
 95% CI (−0.411 to 0.341) −0.54 to 0.316 −0.388 to 0.439 n.a.
p-value 0.832 0.522 0.887  
  1. Correlation coefficient (rho), 95% confidence interval (95% CI), and p-values from non-parametric spearman correlations are indicated
  2. AD Alzheimer’s disease, VaD Vascular dementia, LBD Lewy body diseases, CJD Creutzfeldt-Jakob disease, FTD Fronto-temporal dementia, t-Tau CSF Total tau protein, p-tau CSF Phosphorylated tau protein, Abeta42 CSF beta-amyloid 1-42, Abeta40 CSF beta-amyloid 1-40