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Table 2 Diagnostic accuracy of plasma LCN2

From: Plasma Lipocalin 2 in Alzheimer’s disease: potential utility in the differential diagnosis and relationship with other biomarkers

Diagnostic groups

AUC (95% CI)

P-value

AD vs. HC

0.783 (0.712–0.855)

p < 0.001

AD vs. ND-Dem

0.694 (0.567–0.821)

p = 0.004

AD vs. MD

0.562 (0.349–0.775)

p = 0.591

AD vs. VaD

0.778 (0.667–0.890)

p < 0.001

AD vs. CJD

0.760 (0.685–0.835)

p < 0.001

AD vs. FTD

0.682 (0.571–0.793)

p = 0.004

AD vs. LBD

0.7221 (0.629–0.815)

p < 0.001

  1. HC Healthy controls, ND-Dem Non-neurodegenerative neurological diseases with dementia syndrome, AD Alzheimer’s disease (dementia), MD Mixed dementia (AD plus vascular), VaD Vascular dementia, VCI-MCI Mild vascular cognitive impairment, CJD Creutzfeldt-Jakob disease, FTD Fronto-temporal dementia, LBD Lewy body diseases (dementia with Lewy bodies and Parkinson’s disease dementia), AUC Area under the curve, CI Confidence interval
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Alzheimer's Research & Therapy

ISSN: 1758-9193