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Table 2 Diagnostic accuracy of plasma LCN2

From: Plasma Lipocalin 2 in Alzheimer’s disease: potential utility in the differential diagnosis and relationship with other biomarkers

Diagnostic groups AUC (95% CI) P-value
AD vs. HC 0.783 (0.712–0.855) p < 0.001
AD vs. ND-Dem 0.694 (0.567–0.821) p = 0.004
AD vs. MD 0.562 (0.349–0.775) p = 0.591
AD vs. VaD 0.778 (0.667–0.890) p < 0.001
AD vs. CJD 0.760 (0.685–0.835) p < 0.001
AD vs. FTD 0.682 (0.571–0.793) p = 0.004
AD vs. LBD 0.7221 (0.629–0.815) p < 0.001
  1. HC Healthy controls, ND-Dem Non-neurodegenerative neurological diseases with dementia syndrome, AD Alzheimer’s disease (dementia), MD Mixed dementia (AD plus vascular), VaD Vascular dementia, VCI-MCI Mild vascular cognitive impairment, CJD Creutzfeldt-Jakob disease, FTD Fronto-temporal dementia, LBD Lewy body diseases (dementia with Lewy bodies and Parkinson’s disease dementia), AUC Area under the curve, CI Confidence interval