Cholinergic receptor binding in unimpaired older adults, mild cognitive impairment, and Alzheimer’s disease dementia

Table 2 Overall voxel-wise ANOVA showing the main effects of diagnosis on 2FA binding (V_T/f_p)

Regions	K	P_FWE-corr	F Statistic	Coordinates
R thalamus, R hippocampus, R entorhinal cortex, R insula, R caudate, R putamen	2923	0	32.28	[30, − 10, − 14]
L thalamus, L hippocampus, L entorhinal cortex, L insula, L caudate, L putamen	2127	0	28.56	[− 30, − 14, − 12]
Bilateral anterior cingulate	75	0.003	19.46	[2, 34, 26]
R middle temporal gyrus	21	0.006	18.62	[50, − 24, − 4]

Findings are significant at the voxel level at p < .05 FWE-corrected. K = number of voxels. Coordinates referenced to MNI space

ISSN: 1758-9193