|
Male/female
|
28/14
|
24/4
|
32/0
|
Fisher’s exact test, p < .001
|
|
Age, years
|
72.1 (7.5)
|
74.6 (8.5)
|
79.4 (7.6)
|
F(2,99) = 7.97, p = .001
|
|
Education, years
|
16.1 (2.7)
|
15.4 (2.5)
|
14.8 (3.5)
|
F(2,98) = 1.64, p = .20
|
|
Race/ethnicity, n
| | | |
Fisher’s exact test, p = .75
|
|
African-American
|
9
|
8
|
9
| |
|
White, non-Hispanic
|
30
|
16
|
21
| |
|
Hispanic
|
2
|
2
|
2
| |
|
Asian American/Pacific Islander
|
1
|
2
|
0
| |
|
Duration of dementia, years
|
–
|
–
|
4.8 (3.4)
| |
|
MMSE
|
29.3 (1.1)
|
27.3 (1.9)
|
19.8 (5.0)
|
F(2,99) = 93.06, p < .001
|
|
Dementia Rating Scale total
|
140.0 (3.65)
|
133.1 (7.6)
|
104.5 (24.0)
|
F(2,97) = 60.30, p < .001
|
|
Current medications, n (%)
|
|
Cholinesterase inhibitor
|
1 (2%)
|
8 (29%)
|
23 (72%)
|
Fisher’s exact test, p < .001
|
|
Memantine
|
0 (0%)
|
3 (11%)
|
17 (53%)
|
Fisher’s exact test, p < .001
|
|
Antidepressant
|
6 (14%)
|
9 (32%)
|
12 (38%)
|
Fisher’s exact test, p < .001
|
|
Trails A, s
|
39.5 (12.2)
|
48.3 (16.7)
|
102.6 (62.0)
|
F(2,92) = 28.62, p < .001
|
|
Attention average Z-score
|
− .80 (.61)
|
− 1.36 (.61)
|
− 2.37 (1.19)
|
F(2,92) = 29.25, p < .001
|
|
Immediate Memory average Z-score
|
− .16 (.62)
|
− 1.30 (.75)
|
− 2.30 (.52)
|
F(2,92) = 40.99, p < .001
|
|
Delayed Memory average Z-score
|
.10 (.64)
|
− 1.50 (.63)
|
− 2.49 (.44)
|
F(2,92) = 102.84, p < .001
|
|
Hippocampal volume (% of whole brain)
|
.0050 (.0006)
|
.0046 (.0007)
|
.0038 (.0006)
|
F(2,95) = 30.54, p < .001
|
