Table 1 Characteristics of the study population at T2, n(%), mean±SD
aMCI n=37 | CU n=72 | Total n=109 | p-values | |
|---|---|---|---|---|
KLK8, pg/ml | 911.6±619.8 | 783.1±633.0 | 826.7±628.7 | 0.24 |
Sex | 23 (62.2) | 69 (63.3) | 0.86 | |
Men | 46 (63.9) | |||
Women | 14 (37.8) | 26 (36.1) | 40 (36.7) | |
Age, years | 70.9±8.2 | 71.0±7.9 | 71.0±8.0 | 0.97 |
BMI, kg/m2 | 29.2±5.3 | 28.1±3.3 | 28.5±4.1 | 0.36 |
Years of education | 14.0±2.4 | 14.7±2.4 | 14.5±2.4 | 0.20 |
Smoking status | 16 (43.2) | 49 (45.0) | 0.82 | |
Never | 33 (45.8) | |||
Past | 17 (45.9) | 29 (40.3) | 46 (42.2) | |
Current | 4 (10.8) | 10 (13.9) | 14 (12.8) | |
Sports | 18 (48.6) | 49 (45.0) | 0.58 | |
No | 31 (43.1) | |||
Yes | 19 (51.4) | 41 (56.9) | 60 (55.0) | |
APOE ε4 positive | 0.01 | |||
No | 17 (45.9) | 52 (72.2) | 69 (63.3) | |
Yes | 18 (48.6) | 19 (26.4) | 37 (33.9) | |
Missing | 2 (5.4) | 1 (1.4) | 3 (2.8) | |
z score attention | 9.5±4.2 | 11.3±1.8 | 10.7±2.9 | 0.02 |
z score executive function | 8.7±3.7 | 11.3±1.8 | 10.4±2.9 | <.01 |
z score verbal memory | 5.9±1.1 | 11.2±2.3 | 9.4±3.2 | <.01 |
z score visuoconstruction | 10.3±2.7 | 11.2±1.9 | 10.9±2.3 | 0.11 |
Depressiona | 6 (16.2) | 0 | 6 (5.5) | <.01 |
Missing | 2 (5.4) | 3 (4.2) | 5 | |
Hypertension | 0.82 | |||
No | 27 (73.0) | 54 (75.0) | 81 (74.3) | |
Yes | 10 (27.0) | 18 (25.0) | 28 (25.7) | |
Diabetes mellitus | 0.54 | |||
No | 32 (86.5) | 59 (81.9) | 91 (83.5) | |
Yes | 5 (13.5) | 13 (18.1) | 18 (16.5) | |
Freezing duration, years | 7.5±1.0 | 8.3±0.7 | 8.0±0.9 | <.01 |