Table 4 ADNI participant baseline characteristics

Age (years)

190

75.6 (72.5, 78.4)

197

74.9 (70.2, 79.9)

0.296^a

Male

190

105 (55.3%)

197

132 (67.0%)

0.018^b

Education (years)

190

16.0 (14.0, 18.0)

197

16 (14, 18)

0.538^a

≥ 1 APOE ε4

190

50 (26.3%)

197

103 (52.3%)

<0.001^b

Plasma NfL (pg/mL)

190

29.15 (22.90, 39.15)

197

36.9 (27.600, 48.400)

<0.001^a

Plasma total tau (pg/mL)

190

2.53 (1.78, 3.14)

197

2.62 (1.770, 3.450)

0.324^a

Time since baseline (years)

190

3.0 (3.0, 4.0)

197

3.0 (2.0, 3.1)

<0.001^a

 MMSE

190

29 (29, 30)

197

27 (25, 28)

<0.001^a

 ADAS-Cog13

190

9.50 (6.00, 12.33)

197

19 (14.670, 23.670)

<0.001^a

 Logical Memory - Immediate Recall

190

13 (12, 16)

197

7 (5, 9)

<0.001^a

 Logical Memory - Delayed Recall

190

12 (10, 15)

197

3 (1, 6)

<0.001^a

 Trail Making Test Part B (sec, max 300)

190

80 (62, 100.75)

197

108 (78, 173)

<0.001^a

Hippocampal volume (adjusted for TIV)

190

−0.497 (−0.892, −0.097)

197

−1.379 (−1.975, −0.819)

<0.001^a