Fig. 1
From: P-tau and neurodegeneration mediate the effect of β-amyloid on cognition in non-demented elders
Main effects of Aβ on biomarkers and cognitive measures in non-dementia participants. The figure shows the associations of baseline CSF Aβ42 on longitudinal biomarkers and cognitive measurements in CN and MCI populations, respectively. p values were extracted from linear mixed-effects models adjusted for age, sex, APOE ε4 carrying status, and educational levels. CN, normal controls; MCI mild cognitive impairment; Aβ, amyloid-β; p-tau, phosphorylated tau; t-tau, total tau; NFL, neurofilament light; sTREM2, soluble triggering receptor on myeloid cells 2; MEM, memory function; EF, executive function; LAN, language; VS, visuospatial functioning