Fig. 2

Simulation results by sample size and scenario for symptomatic trials. There are two MMRM tests per facet: categorical time model (lme-cat), red, and continuous time model (lme-slp), purple. The original t test (z test), blue, power calculation is added to each plot. The green (t test) curve represents the simulation results evaluated using a simple t test. The data points were smoothed using the stat smooth command in the ggplot2 R package, with the link function set to probit