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Fig. 6 | Alzheimer's Research & Therapy

Fig. 6

From: Intermittent hypoxia treatment alleviates memory impairment in the 6-month-old APPswe/PS1dE9 mice and reduces amyloid beta accumulation and inflammation in the brain

Fig. 6

Microarray and qPCR analysis of differentially expressed genes in the hippocampus of APP/PS1 mice with IHT 14 days compared to the control ones. a Top enriched GO terms for the differentially expressed genes. b Top enriched KEGG pathways for the differentially expressed genes. The color represents the P-value. c–j were down-regulated genes by the IHT (c) APP, (d) Bace1, (e) PS1, (f) Cdk5, (g) Cdk5r1, (h) Csnk1α1, (i) Csnk1δ, and (j) Capn1. n = 3; *p <0.05; **p < 0.01; ns, not significant

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Alzheimer's Research & Therapy

ISSN: 1758-9193