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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Intermittent hypoxia treatment alleviates memory impairment in the 6-month-old APPswe/PS1dE9 mice and reduces amyloid beta accumulation and inflammation in the brain

Fig. 5

IHT affects the amyloidogenic proteins APP processing. a Representative Western blots of APP, ADAM10, BACE1, Neurofilament-L, PS1, α-Syn, and Aβ. There was a significant increase of ADAM10 (c) and decrease of BACE1 (d) and Neurofilament-L (e) in mouse brain with IHT 14 days compared to the control mice. The expression of APP (b), α-Synuclein (f) and PS1 (g) in brain tissue was not significantly changed by the IHT. n = 6; **p < 0.01; ns, not significant

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