Fig. 4

IHT decreases the levels of Aβ_1-40 (Aβ_1-42) and the pro-inflammatory cytokines in the brain of APP/PS1 mice. Mice with IHT 14 days had reduced levels of Aβ_1-40 (a) and Aβ_1-42 (b), IL-6 (c), and IL-1β (d) in the brain compared to the control mice. However, the level of TNF-α was not changed by the IHT (e). n = 6; *p<0.05; ns, not significant