Table 1 Visual MRI rating unadjusted means and standard deviations by region and group
From: Structural MRI profiles and tau correlates of atrophy in autopsy-confirmed CTE
| Â | Brain donors with CTE | Normal cognition |
|---|---|---|
| Â | Mean (SD) | Mean (SD) |
Orbital-frontal (axial, 0–4 scale) | ||
 N | 40 | 22 |
 Left orbital-frontal | 0.72 (0.78) | 0.32 (0.57) |
 Right orbital-frontal | 0.75 (0.84) | 0.32 (0.57) |
Dorsolateral frontal (axial, 0–4 scale) | ||
 N | 40 | 22 |
 Left dorsolateral frontal | 1.10 (0.93) | 0.73 (0.70) |
 Right dorsolateral frontal | 1.13 (0.91) | 0.73 (0.70) |
Superior frontal (axial, 0–4 scale) | ||
 N | 40 | 22 |
 Left superior frontal | 1.43 (0.90) | 1.18 (0.80) |
 Right superior frontal | 1.48 (0.91) | 1.18 (0.80) |
Anterior temporal lobe (axial, 0–4 scale) | ||
 N | 40 | 22 |
 Left anterior temporal lobe | 1.03 (0.89) | 0.64 (0.79) |
 Right anterior temporal lobe | 1.10 (1.06) | 0.59 (0.85) |
Parietal-occipital (axial, 0–4 scale) | ||
 N | 40 | 22 |
 Left parietal-occipital | 1.72 (1.04) | 1.68 (0.89) |
 Right parietal-occipital | 1.65 (1.00) | 1.68 (0.89) |
Medial temporal lobe (coronal, 0–4 scale) | ||
 N | 24 | 13 |
 Left medial temporal lobe | 1.08 (1.10) | 0.54 (0.66) |
 Right medial temporal lobe | 1.25 (1.03) | 0.69 (0.86) |
Ventricular enlargement (axial, 0–4 scale) | ||
 N | 40 | 22 |
 Left lateral ventricle | 1.57 (0.98) | 1.09 (1.27) |
 Right lateral ventricle | 1.55 (0.99) | 1.09 (1.27) |
 Third ventricle | 1.47 (0.99) | 1.05 (1.21) |
 Fourth ventricle | 0.03 (0.16) | 0.0 |
Corpus callosum (sagittal, 0–4 scale) | ||
 N | 48 | 26 |
 Genu of the corpus callosum | 0.79 (1.03) | 0.65 (0.89) |
 Body of the corpus callosum | 1.19 (1.18) | 1.04 (1.15) |
 Splenium of the corpus callosum | 0.54 (0.82) | 0.31 (0.55) |
Microvascular disease (axial, 0–4 scale) | ||
 N | 43 | 26 |
 Periventricular | 1.86 (0.99) | 1.85 (1.05) |
 Deep white matter | 1.70 (0.96) | 1.73 (0.87) |
Microbleeds, n (%) present | ||
 N | 25 | 22 |
 Deep | 2 (8.0) | 1 (4.5) |
 Frontal lobe | 1 (4.0) | 1 (4.5) |
 Temporal lobe | 1 (4.0) | 1 (4.5) |
 Parietal lobe | 2 (8.0) | 0 |
 Occipital lobe | 0 | 0 |
Cavum septum pellucidum (axial) | N (%) | N (%) |
 N | 40 | 22 |
 Anterior cavum septum pellucidum | 13 (32.5) | 2 (9.1) |
 Posterior cavum septum pellucidum | 4 (10.0) | 0 |