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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: In vivo human molecular neuroimaging of dopaminergic vulnerability along the Alzheimer’s disease phases

Fig. 4

Molecular connectivity of dopaminergic networks in healthy controls and AD. Brain renderings show the molecular structure of the nigrostriatal and mesocorticolimbic dopaminergic networks at p < 0.05, Bonferroni-corrected for multiple comparisons (red edges), and p < 0.01, uncorrected for multiple comparisons (orange edges). Overlap between molecular connectivity networks in healthy controls and each clinical group is also shown on the right, as computed by means of the Dice coefficient. Brain renderings were obtained from the BrainNet Viewer toolbox [35]. Abbreviations: AD-D, Alzheimer’s disease dementia; AD-MCI, mild cognitive impairment due to Alzheimer’s disease; HC, healthy controls

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