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Table 1 Significant clusters of changes in perfusion across all subjects. Probability anatomical mapping and cluster coordinates for significant CBF changes detected when analyzing whole-brain cortical CBF changes (post>pre) across all subjects (upper panel), and for Group 3 participants who received the 4 weeks tACS intervention

From: Impact of multisession 40Hz tACS on hippocampal perfusion in patients with Alzheimer’s disease

All subjects

  

Cluster #1

 

Anatomical probability mapping

Local Maxima Subcluster

t value

 

MNI

 
 

x

y

z

#1

t = 4.64

32

18

-40

R Medial Temporal Pole

#2

t = 3.87

28

2

-44

R Fusiform Gyrus

#3

t = 3.18

26

0

-40

R Entorhinal Cortex

#4

t = 2.96

26

8

-36

R Entorhinal Cortex

#5

t = 2.82

26

16

-40

R Medial Temporal Pole

#6

t = 2.69

32

12

-42

R Medial Temporal Pole

#7

t = 2.66

28

10

-42

R Medial Temporal Pole

Group 3

  

Cluster #1

  

#1

t = 14.66

24

6

-40

R Entorhinal Cortex

#2

t = 12.84

28

8

-42

R Medial Temporal Pole

#3

t = 9.36

26

12

-44

R Fusiform Gyrus

#4

t = 8.54

30

10

-46

R Fusiform Gyrus

#5

t = 8.38

20

8

-40

R Medial Temporal Pole

#6

t = 7.67

28

18

-40

R Medial Temporal Pole

Group 3

  

Cluster #2

  

#1

t = 4.83

-30

-2

-34

L Fusiform Gyrus

#2

t = 4.18

-26

-6

-30

L ParaHippocampal Gyrus

#3

t = 3.77

-28

-14

-26

L Subiculum

#4

t = 3.66

-32

-14

-26

L CA1 (Hippocampus)

#5

t = 3.39

-30

-10

-26

L CA1 (Hippocampus)