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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: The apolipoprotein receptor LRP3 compromises APP levels

Fig. 3

Aβ42 reduces LRP3 expression. a Quantification and western blot showing the expression of LRP3 proteins in neuro-differentiated SH-SY5Y cells treated with 5 μM Aβ42 or scrambled Aβ42 (control). Tubulin was used as an internal control (n = 9 for each condition, *p < 0.05, t-test). b qRT-PCR analysis showing expression of LRP3 mRNA in neuro-differentiated SH-SY5Y cells treated with 500 nM, 1μM, 5 μM Aβ42, or scrambled Aβ42 (control). 18S was used as an internal control for mRNA expression (n = 8 for each condition, p < 0.05; t-test)

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