Fig. 2

Representative MR (A), co-registered PET/MR (B, D) and PET summation images (30–60 min p.i.) (C, E) of one male 21 months old APP/Tau rat (600 g) for [¹¹C]PiB (60.7 MBq) (B, C) and [¹⁸F]THK-5317 (20.2 MBq) (D, E), respectively. Radioactivity is expressed in units of SUV. The outlined regions of interest are shown: frontal cortex (light green), cortex (blue), somatosensory cortex (light blue), hippocampus (pink), thalamus (orange), striatum (nude), hypothalamus (red), brainstem (brown) and cerebellum (yellow)