From: Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease
Inocula | Mice survival (attack rate) STa (n/n0)b | |
---|---|---|
TgMet129 | TgVal129 [8x] | |
Portuguese R136S case | > 650 days (0/5) | > 650 days (0/5) |
Spanish R136S case | > 650 days (0/5) | > 650 days (0/5) |
Sporadic CJD type I (Met129) | 219 ± 17 (6/6)c | 295 ± 21 (6/6)d |
Sporadic CJD type II (Val129) | 618 ± 81 (6/6)c | 228 ± 7 (5/5)d |