Fig. 1

Flowchart of study sample recruitment. ATN classification system (amyloid, tau, neurodegeneration), for “A” (CSF Aβ_1–42), “T” (CSF p-Tau₁₈₁), and “(N)” (CSF t-Tau). CSF, cerebrospinal fluid; CN, cognitive normal; MCI, mild cognitive impairment; AD, Alzheimer’s disease; PET, positron emission tomography; MRI, magnetic resonance imaging; SNAP, suspected non-Alzheimer’s disease pathophysiology