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Table 1 Patient demographics and clinical characteristics

From: Characteristics of behavioral symptoms in right-sided predominant semantic dementia and their impact on caregiver burden: a cross-sectional study

 

AD group (n = 43)

bvFTD group (n = 28)

SD-all group (n = 38)

Comparison among AD, bvFTD, and SD-all groups

SD-R group (n = 14)

SD-L group (n = 24)

Comparison among AD, bvFTD, SD-R, and SD-L groups

H/χ2

p

Post hoc test

H/χ2

p

Post hoc test

Age, years

69.0 (8.5)

63.9 (7.2)

68.1 (6.5)

8.60

0.014a

AD > bvFTD

65.7 (5.7)

69.5 (6.7)

11.33

0.010a

AD > bvFTD

Age of onset, years

65.9 (7.8)

61.4 (7.6)

64.6 (6.9)

6.87

0.032a

AD > bvFTD

61.4 (6.9)

66.5 (6.2)

11.01

0.012a

Not significant

Sex (female)

30 (69.8%)

10 (35.8%)

23 (60.5%)

8.24

0.016b

AD > bvFTD

8 (57.1%)

15 (62.5%)

8.34

0.039b

AD > bvFTD

MMSE (/30)

19.4 (5.5)

18.7 (7.5)

19.4 (7.7)

0.63

0.729a

na

24.0 (3.8)

16.7 (8.1)

11.82

0.008a

SD-R > SD-L, AD

CDR severity

0.8 (0.6)

1.1 (0.8)

0.8 (0.5)

5.10

0.078a

na

0.9 (0.5)

0.7 (0.4)

6.63

0.085a

na

PSMS score (/6)

5.5 (1.2)

4.4 (1.9)

5.6 (1.1)

15.58

<0.001a

SD-all, AD > bvFTD

5.5 (0.9)

5.6 (1.2)

16.30

<0.001a

SD-L, AD > bvFTD

Lawton IADL score (/5)

3.7 (1.1)

3.0 (1.7)

4.5 (0.9)

18.84

<0.001a

SD-all > bvFTD, AD

4.3 (1.1)

4.6 (0.7)

19.44

<0.001a

SD-L > bvFTD, AD

J-ZBI score (/88)

20.0 (13.6)

30.8 (17.2)

17.3 (14.2)

13.30

0.0013a

bvFTD > SD-all, AD

26.3 (17.0)

12.1 (9.3)

21.56

<0.001a

bvFTD > SD-L, AD

SD-R > SD-L

  1. Values are expressed as n or mean (standard deviation). aKruskal-Wallis test. bChi-square
  2. Abbreviations: AD, Alzheimer’s disease; bvFTD, behavioral variant frontotemporal dementia; SD, semantic dementia; SD-R, right-sided predominant semantic dementia; SD-L, left-sided predominant semantic dementia; MMSE, Mini-Mental State Examination; CDR, Clinical Dementia Rating; PSMS, Physical Self-Maintenance Scale; IADL, Instrumental Activities of Daily Living; J-ZBI, Japanese version of the Zarit Burden Interview; na, not available