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Table 3 GLMM outputs of the associations between subjective reports of nocturnal awakenings and the interaction term total tau*middle-to-caudal LC structural integrity, considered bilaterally (model 1), for left LC (model 2), and for right LC (model 3)

From: Associations between locus coeruleus integrity and nocturnal awakenings in the context of Alzheimer’s disease plasma biomarkers: a 7T MRI study

 

Model 1

Model 2

Model 3

Total tau*middle-to-caudal LC integrity

F1,61 = 4.23

p = 0.04

R2β* = 0.06

F1,61 = 4.26

p = 0.04

R2β* = 0.07

F1,59 = 1.96

p = 0.17

Middle-to-caudal LC integrity

F1,61 = 1.47

p = 0.23

F1,61 = 1.55

p = 0.22

F1,59 = 1.20

p = 0.28

Total tau

F1,61 = 3.12

p = 0.08

F1,61 = 3.17

p = 0.08

F1,59 = 1.05

p = 0.31

Age

F1,61 = 4.08

p = 0.05

F1,61 = 5.01

p = 0.03

R2β* = 0.08

F1,59 = 2.61

p = 0.11

Sex

F1,61 = 6.84

p = 0.01

R2β* = 0.10

F1,61 = 7.90

p = 0.007

R2β* = 0.11

F1,59 = 5.59

p = 0.02

R2β* = 0.09

Depression

F1,61 = 7.94

p = 0.007

R2β* = 0.12

F1,61 = 6.64

p = 0.01

R2β* = 0.10

F1,59 = 9.35

p = 0.003

R2β* = 0.14

APOE status

F1,61 = 1.83

p = 0.18

F1,61 = 2.19

p = 0.14

F1,59 = 2.24

p = 0.14