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Table 2 GLMM outputs of the associations between subjective reports of nocturnal awakenings and middle-to-caudal (top) or middle-to-rostral (bottom) LC structural integrity, considered bilaterally (model 1), for left LC (model 2), and for right LC (model 3)

From: Associations between locus coeruleus integrity and nocturnal awakenings in the context of Alzheimer’s disease plasma biomarkers: a 7T MRI study

  Model 1 Model 2 Model 3
Middle-to-caudal LC integrity F1,63 = 5.85
pFDR = 0.03
R2β* = 0.09
F1,63 = 6.73
pFDR = 0.03
R2β* = 0.10
F1,63 = 0.71
pFDR = 0.40
Age F1,63 = 3.27
p = 0.08
F1,63 = 4.08
p = 0.05
F1,63 = 2.20
p = 0.14
Sex F1,63 = 6.67
p = 0.01
R2β* = 0.10
F1,63 = 7.76
p = 0.007
R2β* = 0.11
F1,63 = 6.02
p = 0.02
R2β* = 0.09
Depression F1,63 = 8.07
p = 0.006
R2β* = 0.11
F1,63 = 7.26
p = 0.009
R2β* = 0.10
F1,63 = 8.42
p = 0.005
R2β* = 0.12
APOE status F1,63 = 2.16
p = 0.15
F1,63 = 2.29
p = 0.14
F1,63 = 2.46
p = 0.12
Middle-to-rostral LC integrity F1,63 = 1.37
pFDR = 0.37
F1,63 = 2.03
pFDR = 0.37
F1,62 = 0.36
pFDR = 0.55
Age F1,63 = 2.70
p = 0.11
F1,63 = 2.68
p = 0.11
F1,62 = 2.43
p = 0.12
Sex F1,63 = 6.09
p = 0.02
R2β* = 0.09
F1,63 = 6.60
p = 0.01
R2β* = 0.09
F1,62 = 5.53
p = 0.02
R2β* = 0.08
Depression F1,63 = 7.11
p = 0.01
R2β* = 0.10
F1,63 = 7.40
p = 0.008
R2β* = 0.11
F1,62 = 6.86
p = 0.01
R2β* = 0.10
APOE status F1,63 = 2.38
p = 0.13
F1,63 = 2.43
p = 0.12
F1,62 = 1.90
p = 0.17