Table 2 GLMM outputs of the associations between subjective reports of nocturnal awakenings and middle-to-caudal (top) or middle-to-rostral (bottom) LC structural integrity, considered bilaterally (model 1), for left LC (model 2), and for right LC (model 3)
Model 1 | Model 2 | Model 3 | |
|---|---|---|---|
Middle-to-caudal LC integrity | F1,63 = 5.85 pFDR = 0.03 R2β* = 0.09 | F1,63 = 6.73 pFDR = 0.03 R2β* = 0.10 | F1,63 = 0.71 pFDR = 0.40 |
Age | F1,63 = 3.27 p = 0.08 | F1,63 = 4.08 p = 0.05 | F1,63 = 2.20 p = 0.14 |
Sex | F1,63 = 6.67 p = 0.01 R2β* = 0.10 | F1,63 = 7.76 p = 0.007 R2β* = 0.11 | F1,63 = 6.02 p = 0.02 R2β* = 0.09 |
Depression | F1,63 = 8.07 p = 0.006 R2β* = 0.11 | F1,63 = 7.26 p = 0.009 R2β* = 0.10 | F1,63 = 8.42 p = 0.005 R2β* = 0.12 |
APOE status | F1,63 = 2.16 p = 0.15 | F1,63 = 2.29 p = 0.14 | F1,63 = 2.46 p = 0.12 |
Middle-to-rostral LC integrity | F1,63 = 1.37 pFDR = 0.37 | F1,63 = 2.03 pFDR = 0.37 | F1,62 = 0.36 pFDR = 0.55 |
Age | F1,63 = 2.70 p = 0.11 | F1,63 = 2.68 p = 0.11 | F1,62 = 2.43 p = 0.12 |
Sex | F1,63 = 6.09 p = 0.02 R2β* = 0.09 | F1,63 = 6.60 p = 0.01 R2β* = 0.09 | F1,62 = 5.53 p = 0.02 R2β* = 0.08 |
Depression | F1,63 = 7.11 p = 0.01 R2β* = 0.10 | F1,63 = 7.40 p = 0.008 R2β* = 0.11 | F1,62 = 6.86 p = 0.01 R2β* = 0.10 |
APOE status | F1,63 = 2.38 p = 0.13 | F1,63 = 2.43 p = 0.12 | F1,62 = 1.90 p = 0.17 |