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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Associations between locus coeruleus integrity and nocturnal awakenings in the context of Alzheimer’s disease plasma biomarkers: a 7T MRI study

Fig. 1

Intensity-based cluster analyses of the LC structure. A Cluster analyses on MRI signal intensity within the LC mask revealed two distinct clusters along the LC structure, one covering the middle-to-caudal LC (orange, cluster 1) and the other covering the middle-to-rostral LC (green, cluster 2). B Box plots of MRI signal intensity within clusters 1 and 2, represented by hemisphere. Paired t test analyses showed that MRI signal intensity in cluster 1 is significantly lower than that in cluster 2. *p < .05, **p < .001

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