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Table 4 Analysis of the interpretability based on Kohoutová et al. [23]

From: Machine learning methods for predicting progression from mild cognitive impairment to Alzheimer’s disease dementia: a systematic review

Author (year) Model Feature Biology
SEN/SPE GN AC ST IMP VIS LIT
Plant et al. (2010) [24] - -
Chincarini et al. (2011) [25] - -
Costafreda et al. (2011) [26] -
Filipovych et al. (2011) [27] - -
Hinrichs et al. (2011) [8] - -
Westman et al. (2011) [28] - -
Wolz et al. (2011) [29] - -
Zhang et al. (2011) [30] - - -
Batmanghelich et al. (2012) [31] - - -
Cheng et al. (2012) [32] - - - -
Cho et al. (2012) [33] - -
Gray et al. (2012) [34] -
Li et al. (2012) [35] - -
Toussaint et al. (2012) [36] -
Wee et al. (2012) [37] -
Ye et al. (2012) [38] - - -
Zhang et al. (2012) [9] - -
Adaszewski et al. (2013) [39] - -
Aguilar et al. (2013) [40] - - -
Babu et al. (2013) [41] - - -
Casanova et al. (2013) [42] - - -
Cheng et al. (2013) [43] - - - -
Liu, M. et al. (2013) [44] - - - -
Liu, X. et al. (2013) [45] - -
Wee et al. (2013) [46] - - -
Young et al. (2013) [47] - - - - -
Apostolova et al. (2014) [48] - -
Guerrero et al. (2014) [49] - -
Lebedev et al. (2014) [50] -
Liu, M. et al. (2014) [51] - -
Liu, F. et al. (2014) [52] - - - - -
Min et al. (2014) [53] - - - -
Suk et al. (2014) [54] - -
Tong et al. (2014) [55] -
Cabral et al. (2015) [56] - -
Cheng et al. (2015) [57] - - - -
Cheng et al. (2015) [58] -
Moradi et al. (2015) [59] - - -
Raamana et al. (2015) [60] - -
Ritter et al. (2015) [61] - - -
Salvatore et al. (2015) [62] - -
Xu et al. (2015) [63] - - -
Ardekani et al. (2016) [64] - -
Collij et al. (2016) [66] -
Li et al. (2016) [67] -
Liu et al. (2016) [68] - - -
López et al. (2016) [69] - - -
Suk et al. (2016) [70] -
Thung et al. (2016) [71] - -
Vasta et al. (2016) [72] - -
Zhang et al. (2016) [73] - - -
Zhang et al. (2016) [74] - - -
Ҫitak-Er et al. (2017) [75] - -
Hojjati et al. (2017) [76] -
Long et al. (2017) [77] - - -
Mathotaarachchi et al. (2017) [78] -
Suk et al. (2017) [79] -
Tong et al. (2017) [80] - -
Choi et al. (2018) [81] - -
Donnelly-Kehoe et al. (2018) [82] - -
Gao et al. (2018) [83] - - -
Gómez-Sancho et al. (2018) [84] - - -
Hojjati et al. (2018) [85] - -
Khanna et al. (2018) [86] - - -
Lin et al. (2018) [87] - -
Liu et al. (2018) [88] - -
Liu et al. (2018) [89] - - -
Lu et al. (2018) [90] - - - -
Minhas et al. (2018) [91] - - - -
Popuri et al. (2018) [92] - -
Sorensen et al. (2018) [93] - - - -
Sun et al. (2018) [94] -
Wu et al. (2018) [95] - - -
Yan et al. (2018) [96] - - - -
Basaia et al. (2019) [97] - - -
Cheng et al. (2019) [98] - -
Collazos-Huertas et al. (2019) [99] - -
Elahifasaee et al. (2019) [100] -
Ezzati et al. (2019) [101] - - -
Gupta et al. (2019) [102] - - -
Lee et al. (2019) [103] - -
Lee et al. (2019) [104] - -
Lei et al. (2019) [105] - -
Li et al. (2019) [106]
Li et al. (2019) [107] - - -
Oh et al. (2019) [108] -
Pan et al. (2019) [109] - - - -
Pusil et al. (2019) [110] - - -
Spasov et al. (2019) [111] - - -
Wang et al. (2019) [112] - - -
Wee et al. (2019) [113] -
Xu et al. (2019) [114] -
Zhou et al. (2019) [115] -
Zhu et al. (2019) [116] -
Abrol et al. (2020) [117] -
Gao et al. (2020) [118] - - - -
Giorgio et al. (2020) [119] - - -
Khatri et al. (2020) [120] -
Lin et al. (2020) [121] - - -
Lin et al. (2020) [122] -
Pan et al. (2020) [123] - - - -
Ramon-Julvez et al. (2020) [124] - - - -
Xiao et al. (2020) [125] - - - -
Xu et al. (2020) [126] - -
Yang et al. (2020) [127] - - -
Yee et al. (2020) [128] -
Zhou et al. (2020) [129] -
Bae et al. (2021) [130] - -
Mofrad et al. (2021) [131] - -
Mofrad et al. (2021) [132] - -
Pan et al. (2021) [133] -
Shen et al. (2021) [134] - -
Syaifullah et al. (2021) [135] -
Wen et al. (2021) [136] - -
Zhang et al. (2021) [137] - -
Zhu et al. (2021) [138] -
Total (116) 113 3 60 116 91 51 112
  1. Note. This table shows an interpretability analysis performed for each study selected in our review following the framework proposed by Kohoutová et al. [23]. Presence () or absence (-) of the different sublevels assessments. Behavioral analysis, representational analysis, and invasive studies sub-levels are not applicable to this type of study by its definition. SEN Sensitivity, SPE Specificity, GN Generalizability, AC Analysis of confounds, ST Stability, IMP Importance, VIS Visualization, LIT Literature