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Table 1 Characteristics of the sporadic CAA patients and controls

From: Cerebrospinal fluid levels of the neurotrophic factor neuroleukin are increased in early Alzheimer’s disease, but not in cerebral amyloid angiopathy

  CAA (n = 25) Controls (n = 27) p-value
Age (years) 66 ± 10 63 ± 10 p = 0.32a
Sex, M/F (n) 13/12 12/15 p = 0.59b
MMSE score 28 [26–29]d N.A. -
TP (mg/ml) 0.91 [0.85–0.96] 0.83 [0.78–1.03] p = 0.12c
Aβ40 (pg/ml) 3745 [2200–4694] 6312 [4888–7381] p < 0.0001c
NLK (ng/ml) 3.39 [2.94–4.15] 3.31 [2.41–5.40] p = 0.95c
  1. Values are medians and [IQR] except for age (mean ± SD) and sex (n). TP, NLK, and Aβ40 were measured in CSF
  2. Abbreviations: Aβ40 amyloid beta-40, CAA cerebral amyloid angiopathy, F female, IQR interquartile range, M male, MMSE Mini-Mental State Examination, N.A. not available, NLK neuroleukin, SD standard deviation, TP total protein
  3. aStudent’s t-test
  4. bChi-square test
  5. cMann-Whitney test
  6. dn = 15 patients