|
CAA (n = 25)
|
Controls (n = 27)
|
p-value
|
---|
Age (years)
|
66 ± 10
|
63 ± 10
|
p = 0.32a
|
Sex, M/F (n)
|
13/12
|
12/15
|
p = 0.59b
|
MMSE score
|
28 [26–29]d
|
N.A.
|
-
|
TP (mg/ml)
|
0.91 [0.85–0.96]
|
0.83 [0.78–1.03]
|
p = 0.12c
|
Aβ40 (pg/ml)
|
3745 [2200–4694]
|
6312 [4888–7381]
|
p < 0.0001c
|
NLK (ng/ml)
|
3.39 [2.94–4.15]
|
3.31 [2.41–5.40]
|
p = 0.95c
|
- Values are medians and [IQR] except for age (mean ± SD) and sex (n). TP, NLK, and Aβ40 were measured in CSF
- Abbreviations: Aβ40 amyloid beta-40, CAA cerebral amyloid angiopathy, F female, IQR interquartile range, M male, MMSE Mini-Mental State Examination, N.A. not available, NLK neuroleukin, SD standard deviation, TP total protein
- aStudent’s t-test
- bChi-square test
- cMann-Whitney test
- dn = 15 patients