Fig. 3
Scatter plot of the correlation between CSF NLK levels and YKL-40 levels in a subset (n = 47) of the Barcelona aMCI/AD patients and controls. NLK and YKL-40-levels significantly correlated in the combined aMCI/AD and controls (rSP = 0.51, p < 0.0001, gray line) and in the aMCI/AD patients separately (rSP = 0.79, p < 0.0001, black dots and black line), but not in the controls (rSP = 0.033, p = 0.87, white dots, dotted line). Abbreviations: AD, Alzheimer’s dementia; rSP, Spearman rank coefficient; aMCI, amnestic mild cognitive impairment; NLK, neuroleukin; YKL-40, chitinase-3 like-protein 1