Skip to main content

Table 4 Number of patients in each category of CIBIC-Plus

From: Intracerebroventricular injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer’s disease dementia: a phase I clinical trial

  Baseline Week 4 Week 8 Week 12
Low dose High dose Low dose High dose Low dose High dose Low dose High dose
Marked worsening         
Moderate worsening     1   1   3
Minimal worsening   2 2    1   
No change 3 3   2   2 2 1
Minimal improvement   1 1 1 2 2 1 1
Moderate improvement     1 1    1
Marked improvement     1     
  1. CIBIC-Plus, Clinician’s Interview-Based Impression of Change Plus Caregiver Input