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Table 4 Number of patients in each category of CIBIC-Plus

From: Intracerebroventricular injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer’s disease dementia: a phase I clinical trial

 

Baseline

Week 4

Week 8

Week 12

Low dose

High dose

Low dose

High dose

Low dose

High dose

Low dose

High dose

Marked worsening

        

Moderate worsening

   

1

 

1

 

3

Minimal worsening

 

2

2

  

1

  

No change

3

3

 

2

 

2

2

1

Minimal improvement

 

1

1

1

2

2

1

1

Moderate improvement

   

1

1

  

1

Marked improvement

   

1

    
  1. CIBIC-Plus, Clinician’s Interview-Based Impression of Change Plus Caregiver Input