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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Intracerebroventricular injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer’s disease dementia: a phase I clinical trial

Fig. 1

Study flow diagram for a phase I protocol in participants with Alzheimer’s disease. A Participants underwent three repeated hUCB-MSC injections in a dose-escalating, open-label fashion with two sequential doses (1.0 × 107 cells/2 mL in the low dose [LD] group and 3.0 × 107 cells/2 mL in the high dose [HD] group). Before continuing the study with subsequent participants, we confirmed that there was no DLT. Empty arrows indicate hUCB-MSC injection. B Schematic drawing of right intracerebroventricular injection of hUCB-MSCs via the Ommaya reservoir

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Alzheimer's Research & Therapy

ISSN: 1758-9193