Cardiovascular Risk Factors, Aging and Dementia (CAIDE) score | Australian National University Alzheimer’s Disease Risk Index (ANU-ADRI) | Brief Dementia Screening Indicator (BDSI) | |
---|---|---|---|
Development sample age range | 39–64 | Variable (population based) | 65+ |
Development sample size | 1409 | 903–2496 | 1125–13889 |
Mean length of follow-up, years | 21 | Variable (population based) | 6 |
Accuracy (area under the curve or C-statistic)** | 0.77–0.78 | 0.64–0.74 | 0.68–0.78 |
Demographic predictors | |||
Age | ● | ● | ● |
Sex | ● | ● | |
Education* | ● | ● | ● |
Functional impairment | |||
Difficulty with instrumental activities of daily living | ● | ||
Health predictors | |||
Systolic blood pressure* | ● | ||
Body mass index* | ● | ● | |
Total cholesterol | ● | ||
Diabetes* | ● | ● | |
Stroke | ● | ||
Traumatic brain injury* | ● | ||
Depression*/depressive symptoms | ● | ● | |
Lifestyle predictors | |||
Smoking* | ● | ||
Physical activity* | ● | ● | |
Social isolation* | ● | ||
Cognitively stimulating activities | ● | ||
Alcohol* | ● | ||
Fish intake | ● | ||
Genetic predictors | |||
APOE e4 carrier | ● |