Skip to main content
Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer’s disease

Fig. 4

Relation between plasma and CSF predictors of AD. Partial least square discriminant analysis (PLS-DA) of AD vs control, utilizing metabolites from both plasma and CSF in predicted fasted samples. Treatment group discrimination is shown by the SCORES (inset) with a plain of discrimination indicated by a dashed red line, while metabolites weighting in group discrimination are shown by the LOADINGS. Loading node color indicates metabolite origin (pink for plasma and blue for CSF). Loading node size indicates metabolite variable importance in projection (i.e., VIP). Analysis was performed with all measured metabolites, including specific ratios, but only those with VIP ≥ 1.4 are displayed for clarity purpose

Back to article page