Skip to main content

Table 4 Associations between LTRA use and cognitive test performance over time in the AD dementia group

From: Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer’s dementia

  n RR or Β [95% CI] β [95% CI] z or t p value
User Non-user
Logical memory
 Immediate memory 141 419 RR = 1.048 [0.972, 1.130] - 1.22 .2230
 Delayed memory 140 416 RR = 1.065 [0.932, 1.217] - 0.93 .3550
Psychomotor processing speed
 Digit Symbol Substitution Test 112 330 B = 1.466 [0.253, 2.678] 0.100 [0.017, 0.182] 2.37 .0192*
Language
 Boston Naming Test 141 420 B = 0.529 [0.005, 1.053] 0.069 [0.001, 0.137] 1.98 .0492*
 Animal naming 143 423 B = 0.541 [0.215, 0.866] 0.101 [0.040, 0.162] 3.26 .0014*
 Vegetable naming 143 422 B = 0.309 [0.056, 0.561] 0.079 [0.015, 0.143] 2.40 .0176*
  1. RR rate ratio, B unstandardized coefficient, z for logical memory, and t for all other tests
  2. *Significant at FDR 0.1