Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer’s dementia

Table 4 Associations between LTRA use and cognitive test performance over time in the AD dementia group

	n		RR or Β [95% CI]	β [95% CI]	z or t	p value
	User	Non-user	RR or Β [95% CI]	β [95% CI]	z or t	p value
Logical memory
Immediate memory	141	419	RR = 1.048 [0.972, 1.130]	-	1.22	.2230
Delayed memory	140	416	RR = 1.065 [0.932, 1.217]	-	0.93	.3550
Psychomotor processing speed
Digit Symbol Substitution Test	112	330	B = 1.466 [0.253, 2.678]	0.100 [0.017, 0.182]	2.37	.0192*
Language
Boston Naming Test	141	420	B = 0.529 [0.005, 1.053]	0.069 [0.001, 0.137]	1.98	.0492*
Animal naming	143	423	B = 0.541 [0.215, 0.866]	0.101 [0.040, 0.162]	3.26	.0014*
Vegetable naming	143	422	B = 0.309 [0.056, 0.561]	0.079 [0.015, 0.143]	2.40	.0176*

RR rate ratio, B unstandardized coefficient, z for logical memory, and t for all other tests
^*Significant at FDR 0.1

ISSN: 1758-9193