Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer’s dementia

Table 3 Associations between LTRA use and cognitive test performance over time in the MCI group

	n		RR or Β [95% CI]	β [95% CI]	z or t	p value
	User	Non-user	RR or Β [95% CI]	β [95% CI]	z or t	p value
Logical memory
Immediate memory	197	582	RR = 1.015 [0.991, 1.039]	-	1.24	.2150
Delayed memory	197	581	RR = 1.032 [0.993, 1.074]	-	1.59	.1120
Psychomotor processing speed
Digit Symbol Substitution Test	150	431	B = 0.690 [0.035, 1.344]	0.055 [0.003, 0.107]	2.07	.0400
Language
Boston Naming Test	197	584	B = 0.189 [−0.049, 0.427]	0.035 [−0.009, 0.079]	1.55	.1210
Animal naming	197	584	B = 0.189 [−0.043, 0.421]	0.034 [−0.008, 0.075]	1.59	.1120
Vegetable naming	197	581	B = 0.035 [−0.129, 0.200]	0.001 [−0.030, 0.047]	0.42	.6755

RR rate ratio, B unstandardized coefficient, z for logical memory, and t for all other tests
^*Significant at FDR 0.1

ISSN: 1758-9193