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Table 2 Associations between LTRA use and cognitive test performance over time in the normal cognition group

From: Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer’s dementia

  n RR or Β [95% CI] β [95% CI] z or t p value
User Non-user
Logical memory
 Immediate memory 345 1040 RR = 0.992 [0.985, 0.998] - −2.55 .0106*
 Delayed memory 345 1040 RR = 0.995 [0.987, 1.002] - −1.24 .2134
Psychomotor processing speed
 Digit Symbol Substitution Test 278 742 B = 0.158 [−0.099, 0.414] 0.012 [−0.007, 0.031] 1.21 .2284
Language
 Boston Naming Test 344 1041 B = −0.020 [−0.081, 0.041] −0.007 [−0.026, 0.013] −0.65 .5134
 Animal naming 345 1043 B = 0.046 [−0.056, 0.148] 0.008 [−0.011, 0.026] 0.88 .3773
 Vegetable naming 345 1039 B = −0.017 [−0.093, 0.062] −0.004 −0.021, 0.014] −0.40 .6912
  1. Abbreviations: RR rate ratio, B unstandardized coefficient, z for logical memory, and t for all other tests
  2. Significant at FDR 0.1