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Table 2 Associations between LTRA use and cognitive test performance over time in the normal cognition group

From: Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer’s dementia

 

n

RR or Β [95% CI]

β [95% CI]

z or t

p value

User

Non-user

Logical memory

 Immediate memory

345

1040

RR = 0.992 [0.985, 0.998]

-

−2.55

.0106*

 Delayed memory

345

1040

RR = 0.995 [0.987, 1.002]

-

−1.24

.2134

Psychomotor processing speed

 Digit Symbol Substitution Test

278

742

B = 0.158 [−0.099, 0.414]

0.012 [−0.007, 0.031]

1.21

.2284

Language

 Boston Naming Test

344

1041

B = −0.020 [−0.081, 0.041]

−0.007 [−0.026, 0.013]

−0.65

.5134

 Animal naming

345

1043

B = 0.046 [−0.056, 0.148]

0.008 [−0.011, 0.026]

0.88

.3773

 Vegetable naming

345

1039

B = −0.017 [−0.093, 0.062]

−0.004 −0.021, 0.014]

−0.40

.6912

  1. Abbreviations: RR rate ratio, B unstandardized coefficient, z for logical memory, and t for all other tests
  2. Significant at FDR 0.1