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Fig. 8 | Alzheimer's Research & Therapy

Fig. 8

From: High-fat diet-induced atherosclerosis promotes neurodegeneration in the triple transgenic (3 × Tg) mouse model of Alzheimer’s disease associated with chronic platelet activation

Fig. 8

Increased loss of neurons in the hippocampus of HFD-treated 3 × Tg mice. a Representative immunohistochemical images of neurons at different hippocampal subregions stained with anti-NeuN antibody. Scale bar, 50 μm. b Quantification of the numbers of NeuN-positive neurons at different hippocampal subregions (n = 3/group). Data are expressed as mean ± SD, unpaired Student t test, two-tailed. **p < 0.01; ***p < 0.001; n.s., not significant

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