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Table 1 Characteristics of participants at baseline (n = 297), COGICARE study

From: Dynamic reciprocal relationships between cognitive and functional declines along the Alzheimer’s disease continuum in the prospective COGICARE study

  CN MCI AD All
  (N = 102) (N = 123) (N = 72) (N = 297)
Age in years: median (min–max) 83.4 (75.6–92.8) 82.0 (74.2–95.2) 84.4 (76.0–93.5) 82.9 (74.2–95.2)
Male sex (%) 32.35 41.46 34.72 36.70
Education level higher than primary school (%) 77.45 65.85 62.50 69.02
ApoE4 carriers (%) 14.71 13.82 36.11 19.53
Limitation in activities of daily living (%):     
Bathing
 No limitation 96.08 95.93 66.67 88.89
 Partial limitation 1.96 2.44 16.67 5.72
 Total limitation 1.96 1.63 16.67 5.39
Dressing
 No limitation 96.08 97.56 73.61 91.25
 Partial limitation 0.98 1.63 13.89 4.38
 Total Limitation 2.94 0.81 12.50 4.38
Toileting
 No limitation 100.00 99.19 95.83 98.65
 Partial limitation 0.00 0.00 4.17 1.01
 Total limitation 0.00 0.81 0.00 0.34
Transfering
 No limitation 99.02 99.19 94.44 97.98
 Partial limitation 0.98 0.81 5.56 2.02
 Total limitation 0.00 0.00 0.00 0.00
Eating
 No limitation 99.02 100.00 95.83 98.65
 Partial limitation 0.98 0.00 4.17 1.35
 Total limitation 0.00 0.00 0.00 0.00
Limitation in instrumental activities of daily living (%):
Telephone use
 No limitation 100.00 95.12 56.94 87.54
 Partial limitation 0.00 4.88 36.11 10.77
 Total limitation 0.00 0.00 6.94 1.68
Shopping
 No limitation 78.43 77.24 36.11 67.68
 Partial limitation 13.73 19.51 26.39 19.19
 Total limitation 7.84 3.25 37.50 13.13
Transportation     
 No limitation 79.41 83.74 44.44 72.73
 Partial limitation 19.61 15.45 48.61 24.92
 Total limitation 0.98 0.81 6.94 2.36
Medication
 No limitation 99.02 95.12 48.61 85.19
 Partial limitation 0.00 4.07 25.00 7.74
 Total limitation 0.98 0.81 26.39 7.07
Finances
 No limitation 89.22 86.99 41.67 76.77
 Partial limitation 10.78 11.38 26.39 14.81
 Total limitation 0.00 1.63 31.94 8.42
Cognitive scores: median (min–max)     
 MMSE 28 (17–30) 27 (20–30) 23 (11–28) 27 (11–30)
 IST 45 (22–82) 39 20–61) 29 (12–62) 39 (12–82)
 BVRT 12 (6–15) 11 (5–15) 9 (5–14) 11 (5–15)
 TMT-B 26.5 (3.0–60.0) 21.3 (0.5–62.6) 7.3 (0.7–40.0) 20.0 (0.5–62.6)
Limitation score: median (min–max) 0 (0–7) 0 (0–14) 3 (0–13) 0 (0–14)
Number of measures by subject over follow-up: median (min–max)   
 MMSE 5 (2–6) 5 (2–7) 4 (1–7) 5 (1–7)
 IST 4 (1–6) 5 (1–7) 4 (1–7) 4 (1–7)
 BVRT 2 (1–4) 5 (2–6) 3 (1–7) 3 (1–7)
 TMT-B 2 (1–2) 1 (1–2) 1 (1–2) 1 (1–2)
 Limitations 5 (2–6) 5 (2–7) 5 (2–7) 5 (2–7)