Table 2 Performance of the linear and gradient boosting regressions, predicting change in MMSE 2 and 4 years after baseline for three different cohort selections. We compare models trained on features a) the all features set from baseline and b) from baseline cognitive scores only
From: Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease
R2 (SD) | 2-year follow-up | 4-year follow-up |
|---|---|---|
All features | ||
LR, Aβ only | 0.372 (0.081) | 0.205 (0.227) |
LR, all subjects | 0.354 (0.083) | 0.325 (0.134) |
LR, all subjects, weighted | 0.388 (0.073) | 0.304 (0.152) |
GB, Aβ only | 0.287 (0.124) | 0.156 (0.244) |
GB, all subjects | 0.356 (0.108) | 0.252 (0.191) |
GB, all subjects, weighted | 0.338 (0.950) | 0.263 (0.192) |
Cognitive tests only | ||
LR, Aβ only | 0.343 (0.087) | 0.178 (0.203) |
LR, all subjects | 0.333 (0.081) | 0.228 (0.143) |
LR, all subjects, weighted | 0.350 (0.079) | 0.225 (0.160) |
GB, Aβ only | 0.272 (0.133) | − 0.050 (0.358) |
GB, all subjects | 0.323 (0.118) | 0.149 (0.224) |
GB, all subjects, weighted | 0.293 (0.114) | 0.118 (0.227) |